Bubble Up Pizza Casserole
Bubble Up Pizza Casserole makes every bite a delightful experience that captures the essence of your favorite pizza in a fun, unique way. Imagine soft, fluffy biscuit pieces enveloped in rich pizza sauce, all layered with gooey, melty cheese and topped with savory pepperoni. This dish not only satisfies your pizza cravings but also offers comfort on a chilly night or a bustling weeknight. It’s a wholesome dinner option that truly embodies the best of American cuisine while delivering a delightful taste adventure right at home.

The first time I made this casserole, I was astounded by how something so simple could deliver such a satisfying result. Bubble Up Pizza Casserole brings together all that we love about traditional pizza but in a cozy, casserole style. It’s perfect for family dinners, sleepovers, or even casual gatherings with friends. You won’t need to stress about complicated steps or hard-to-find ingredients, as this dish is crafted with readily available items. So roll up your sleeves, gather your loved ones, and get ready to savor every cheesy, meaty bite!
Table of Contents
Why You’ll Love This Recipe
- Simple & Quick: In just 10 minutes of prep and about 35 minutes of baking, you can put this tasty dish on the table, making it perfect for busy nights.
- Irresistible Flavor: The combination of crispy biscuit dough, zesty pizza sauce, and melted cheese creates a flavor explosion that hits all the right notes.
- Eye-Catching Appeal: This casserole isn’t just delicious; it comes out of the oven golden and bubbling, making it a feast for the eyes as well.
- Flexible Serving: Whether it’s a comforting dinner, party snack, or even breakfast indulgence, this casserole adapts beautifully to any occasion.
- Diet-Friendly Options: Consider swapping out ingredients for dietary preferences, like using turkey sausage or dairy-free cheese if needed.

Ingredients You’ll Need
- 1 lb ground Italian sausage: This is the heart of the dish, infusing it with rich, savory flavors. You can swap it for turkey sausage or a meat alternative if desired.
- 1 15 oz jar pizza sauce: Choose your favorite brand or even make homemade pizza sauce for an extra special touch. The sauce brings everything together and adds that classic pizza flavor.
- 1 16.3 oz tube refrigerated Pillsbury Grands biscuits: These biscuits are crucial for that fluffy, comforting texture. If you prefer, you can try making your own biscuit dough.
- 2 cups shredded mozzarella cheese: The classic pizza cheese! It melts beautifully and gives that cheesy pull that everyone loves. For a twist, mix in some cheddar or provolone.
- Pepperoni slices: Optional but adds fantastic flavor and nostalgia. Feel free to replace with veggies or omit for a lighter version.
- Italian seasoning (optional): Sprinkle this on top for a touch of herbal aroma and flavor. It enhances the overall taste but is not necessary.
How to Make Bubble Up Pizza Casserole
Brown the sausage: If you’re using raw ground Italian sausage, hot or mild depending on your preference, start by browning it in a large skillet over medium heat. Once it’s fully cooked and crumbled, drain the excess fat and set it aside.
Prepare the biscuits: Open the 16.3 oz tube of refrigerated Pillsbury Grands biscuits. Carefully separate them, and then cut each biscuit into eighths. This will create bite-sized pieces that will become perfectly fluffy in the oven.
Mix it all together: In a large bowl, combine the cooked sausage, cut biscuit pieces, and 1 jar (15 oz) of pizza sauce. Stir until everything is well-coated and evenly mixed. The texture should feel hearty, with every piece getting its fair share of those delicious flavors.
Spread in a baking dish: Lightly grease a 9×13 inch baking dish with non-stick cooking spray. Pour the biscuit and sausage mixture into the dish, spreading it evenly across the bottom. This step is crucial for ensuring even cooking and avoiding any sogginess.
Top with cheese and pepperoni: Grab 2 cups of shredded mozzarella cheese and sprinkle it generously over the mixture. Top with pepperoni slices as desired; you can add as many or as few as you want. If you’re feeling adventurous, try layering in some vegetables here as well!
Season if you’d like: To elevate the aroma and flavor, sprinkle a little Italian seasoning over the top. This extra touch can make all the difference and is totally optional based on your flavor preferences.
Bake to perfection: Preheat your oven to 375°F and place the baking dish uncovered in the oven. Bake for about 25-30 minutes until the edges turn golden and the biscuits are cooked through. Your kitchen will be filled with wonderful aromas, and you’ll know it’s almost time to enjoy!
Storing & Reheating
To store your Bubble Up Pizza Casserole, let it cool completely after baking. Then, cover it tightly with plastic wrap or transfer portions into an airtight container. At room temperature, it can sit for a couple of hours; in the fridge, it lasts for up to 3 days. For longer storage, freeze it for a maximum of 3 months. When ready to enjoy, reheat in the microwave for about 2-3 minutes or warm it up in the oven at 350°F for 10-15 minutes. Just remember, the texture won’t be quite the same as when freshly baked, but it will still be delicious!
Chef’s Helpful Tips
- Be sure to cook the sausage fully before mixing it with the other ingredients; this helps prevent any sogginess.
- Maintain equal-sized biscuit pieces for even baking; this ensures every bite is perfect.
- If you like your cheese extra crispy, add it in later during the last 5-10 minutes of baking.
- Consider adding your favorite veggies such as bell peppers, onions, or even olives for extra flavor and nutrition.
- If making ahead, prep all the ingredients and store them in the fridge, then just assemble and bake when you’re ready.
The beauty of Bubble Up Pizza Casserole is its adaptability; feel free to switch ingredients based on what you have at hand. It’s such a relief knowing that you can whip this up quickly for a family dinner, and it’s sure to please even the pickiest eaters.
Recipe FAQs
Can I use a different type of meat in this casserole?
How can I make this dish vegetarian?
Can I freeze this Pizza Casserole?
What can I serve with Bubble Up Pizza Casserole?
More Dinner Recipes
- Vegan Crab Cakes
- Slow Cooker Cranberry Sauce
- Italian Sausage Lasagna
- Slow Cooker Ground Beef Stroganoff
- Soft & Fluffy Homemade Sandwich Bread
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Bubble Up Pizza Casserole
- Prep Time: 10 minutes
- Cook Time: 35 minutes
- Total Time: 45 minutes
- Yield: 6 servings 1x
- Category: Dinner
- Method: Baking
- Cuisine: Italian
Description
Enjoy the savory flavors of Bubble Up Pizza Casserole, a quick and tasty dish featuring layers of ground sausage, pizza sauce, and melty mozzarella. It’s a comforting meal that brings joy to any dinner table!
Ingredients
- 1 lb ground italian sausage
- 1 15 oz jar pizza sauce
- 1 16.3 oz tube refrigerated pillsbury grands biscuits
- 2 cups shredded mozzarella cheese
- pepperoni slices
- italian seasoning optional
Instructions
- Brown the ground sausage in a pan until fully cooked and crumbled. Drain any excess fat.
- Separate the biscuits and cut each biscuit into eighths.
- In a mixing bowl, combine the cooked sausage, cut biscuits, and pizza sauce. Stir well to mix everything together.
- Spread the mixture evenly in a lightly greased 9×13 baking dish.
- Top the mixture with shredded mozzarella cheese and pepperoni slices.
- If desired, sprinkle a bit of Italian seasoning on top.
- Bake uncovered at 375 degrees Fahrenheit for 25-30 minutes, or until the biscuits are cooked through.
Notes
For extra flavor, try adding your favorite vegetables or spices to the mixture.
This casserole can be made ahead of time and refrigerated. Just reheat before serving.
Feel free to substitute the sausage with ground turkey or chicken for a lighter option.
Nutrition
- Serving Size: 1/6 of casserole
- Calories: 350
- Sugar: 2g
- Sodium: 700mg
- Fat: 22g
- Saturated Fat: 9g
- Unsaturated Fat: 12g
- Trans Fat: 0g
- Carbohydrates: 25g
- Fiber: 1g
- Protein: 15g
- Cholesterol: 65mg




